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KMID : 0383820120720010024
Tuberculosis and Respiratory Diseases
2012 Volume.72 No. 1 p.24 ~ p.29
Annual Change of Peak Expiratory Flow Rate in Asthma and COPD
Hong Sung-Chul

Lee Cho-I
Han Jang-Soo
Kim Won-Dong
Lee Kye-Young
Kim Sun-Jong
Kim Hee-Joung
Ha Kyung-Won
Chon Gyu-Rak
Yoo Kwang-Ha
Abstract
Background : Measurement of peak expiratory flow rate (PEFR) in a follow-up examination for a chronic airway disease is useful because it has the advantages of being a simple measurement and can be repeated during examination. The aim of this study was to examine the annual decrease of PEFR in asthma and chronic obstructive pulmonary disease (COPD) patients and to confirm the factors which influence this decrease.

Materials and Methods : From May, 2003 to September, 2010, the annual decrease of PEFR was obtained from asthma and COPD patients attending an outpatient pulmonary clinic. PEFR was measured using a Mini-Wright peak flow meter (Clement Clarke International Ltd. UK), and we conducted an analysis of factors that influence the change of PEFR and its average values.

Results : The results showed an annual decrease of 1.70¡¾12.86 L/min the asthmatic patients and an annual decrease of 10.3¡¾7.32 L/min in the COPD patients. Age and FEV1 were the predictive factors influencing change in asthma, and FEV1 and smoking were the predictive factors influencing change in COPD.

Conclusion : We confirmed the annual decreasing PEFR in patients with chronic airway disease and identified factors that work in conjunction with FEV1 to influence the change.
KEYWORD
Forced Expiratory Volume, Pulmonary Disease, Chronic Obstructive, Asthma, Peak Expiratory Flow Rate
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